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1

Estimation of safe dietary intake levels of acrylamide for humans

Robert G. Tardiff, Michael L. Gargas, Christopher R. Kirman, M. Leigh Carson, Lisa M. Sweeney

Journal:

Food and Chemical Toxicology

Year:

2010

Language:

english

File:

PDF, 334 KB

english, 2010

2

Evaluation of NHANES biomonitoring data for volatile organic chemicals in blood: Application of chemical-specific screening criteria

Kirman, Christopher R, Aylward, Lesa L, Blount, Ben C, Pyatt, David W, Hays, Sean M

Journal:

Journal of Exposure Science and Environmental Epidemiology

Year:

2012

Language:

english

File:

PDF, 516 KB

english, 2012

3

Comparison of Toxicity and Recovery in the Duodenum of B6C3F1 Mice Following Treatment with Intestinal Carcinogens Captan, Folpet, and Hexavalent Chromium

Thompson, Chad M., Wolf, Jeffrey C., McCoy, Alene, Suh, Mina, Proctor, Deborah M., Kirman, Christopher R., Haws, Laurie C., Harris, Mark A.

Journal:

Toxicologic Pathology

Year:

2017

Language:

english

File:

PDF, 2.29 MB

english, 2017

4

Improving Cancer Dose–Response Characterization by Using Physiologically Based Pharmacokinetic Modeling: An Analysis of Pooled Data for Acrylonitrile-Induced Brain Tumors to Assess Cancer Potency in the Rat

Christopher R. Kirman, Sean M. Hays, Gregory L. Kedderis, Michael L. Gargas, Dale E. Strother

Journal:

Year:

2000

Language:

english

File:

PDF, 274 KB

english, 2000

5

Development of a physiologically-based toxicokinetic model of acrylamide and glycidamide in rats and humans

Lisa M. Sweeney, Christopher R. Kirman, Michael L. Gargas, M. Leigh Carson, Robert G. Tardiff

Journal:

Food and Chemical Toxicology

Year:

2010

Language:

english

File:

PDF, 719 KB

english, 2010

6

Evaluation of urinary speciated arsenic in NHANES: Issues in interpretation in the context of potential inorganic arsenic exposure

Aylward, Lesa L., Ramasamy, Santhini, Hays, Sean M., Schoeny, Rita, Kirman, Christopher R.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2014

Language:

english

File:

PDF, 593 KB

english, 2014

7

Estimation of interindividual variation in oxidative metabolism of dichloromethane in human volunteers

Lisa M. Sweeney, Christopher R. Kirman, David A. Morgott, Michael L. Gargas

Journal:

Toxicology Letters

Year:

2004

Language:

english

File:

PDF, 598 KB

english, 2004

8

Evaluation of Biomonitoring Data from the CDC National Exposure Report in a Risk Assessment Context: Perspectives across Chemicals

Aylward, Lesa L., Kirman, Christopher R., Schoeny, Rita, Portier, Christopher J., Hays, Sean M.

Journal:

Environmental Health Perspectives

Year:

2012

Language:

english

File:

PDF, 737 KB

english, 2012

9

2,4-D Exposure and risk assessment: Comparison of external dose and biomonitoring based approaches

Hays, Sean M., Aylward, Lesa L., Driver, Jeffrey, Ross, John, Kirman, Christopher

Journal:

Regulatory Toxicology and Pharmacology

Year:

2012

Language:

english

File:

PDF, 223 KB

english, 2012

10

Risk assessments for chronic exposure of children and prospective parents to ethylbenzene (CAS No. 100-41-4)

Sweeney, Lisa M., Kester, Janet E., Kirman, Christopher R., Gentry, P. Robinan, Banton, Marcy I., Bus, James S., Gargas, Michael L.

Journal:

Critical Reviews in Toxicology

Year:

2015

Language:

english

File:

PDF, 3.08 MB

english, 2015

11

1,3-Butadiene: II. Genotoxicity profile

Albertini, Richard J., Carson, M. Leigh, Kirman, Christopher R., Gargas, Michael L.

Journal:

Critical Reviews in Toxicology

Year:

2010

Language:

english

File:

PDF, 1.46 MB

english, 2010

12

Risk assessment and Biomonitoring Equivalent for 2-ethylhexyl-2,3,4,5 tetrabromobenzoate (TBB) and tetrabromobenzoic acid (TBBA).

Hays, Sean M., Kirman, Christopher R.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2017

Language:

english

File:

PDF, 593 KB

english, 2017

13

Contribution of trichloroacetic acid to liver tumors observed in perchloroethylene (perc)-exposed mice

Lisa M. Sweeney, Christopher R. Kirman, Michael L. Gargas, Paul H. Dugard

Journal:

Year:

2009

Language:

english

File:

PDF, 760 KB

english, 2009

14

Quantitative Property–Property Relationship for Screening-Level Prediction of Intrinsic Clearance: A Tool for Exposure Modeling for High-Throughput Toxicity Screening Data

Kirman, Christopher R., Aylward, Lesa L., Wetmore, Barbara A., Thomas, Russell S., Sochaski, M., Ferguson, Stephen S., Csiszar, Susan A., Jolliet, Olivier

Journal:

Applied In Vitro Toxicology

Year:

2015

Language:

english

File:

PDF, 283 KB

english, 2015

15

Oral Reference Dose for ethylene glycol based on oxalate crystal-induced renal tubule degeneration as the critical effect

Snellings, William M., Corley, Richard A., McMartin, Kenneth E., Kirman, Christopher R., Bobst, Sol M.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2013

Language:

english

File:

PDF, 493 KB

english, 2013

16

Reduction of hexavalent chromium by fasted and fed human gastric fluid. II. Ex vivo gastric reduction modeling

Kirman, Christopher R., Suh, Mina, Hays, Sean M., Gürleyük, Hakan, Gerads, Russ, De Flora, Silvio, Parker, William, Lin, Shu, Haws, Laurie C., Harris, Mark A., Proctor, Deborah M.

Journal:

Toxicology and Applied Pharmacology

Year:

2016

Language:

english

File:

PDF, 1.15 MB

english, 2016

17

Biomonitoring Equivalents (BEs) for tetrabromobisphenol A

Hays, Sean M., Kirman, Christopher R.

Journal:

Regulatory Toxicology and Pharmacology

Year:

2018

Language:

english

File:

PDF, 650 KB

english, 2018

18

A chronic oral reference dose for hexavalent chromium-induced intestinal cancer

Thompson, Chad M., Kirman, Christopher R., Proctor, Deborah M., Haws, Laurie C., Suh, Mina, Hays, Sean M., Hixon, J. Gregory, Harris, Mark A.

Journal:

Journal of Applied Toxicology

Year:

2014

Language:

english

File:

PDF, 665 KB

english, 2014

19

Integration of mechanistic and pharmacokinetic information to derive oral reference dose and margin-of-exposure values for hexavalent chromium

Thompson, Chad M., Kirman, Christopher R., Hays, Sean M., Suh, Mina, Harvey, Seneca E., Proctor, Deborah M., Rager, Julia E., Haws, Laurie C., Harris, Mark A.

Journal:

Journal of Applied Toxicology

Year:

2017

Language:

english

File:

PDF, 775 KB

english, 2017

20

Corrigendum to: Derivation of a drinking water equivalent level (DWEL) related to the maximum contaminant level goal for perfluorooctanoic acid (PFOA), a persistent water soluble compound [47 (10) 2557–2589]

Robert G. Tardiff, M. Leigh Carson, Lisa M. Sweeney, Christopher R. Kirman, Yu-Mei Tan

Journal:

Food and Chemical Toxicology

Year:

2010

Language:

english

File:

PDF, 105 KB

english, 2010

21

A Physiologically Based Pharmacokinetic Model for Acrylamide and Its Metabolite, Glycidamide, in the Rat

Kirman, Christopher, Gargas, Michael, Deskin, Randy, Tonner-Navarro, Lisa, Andersen, Melvin

Journal:

Journal of Toxicology and Environmental Health

Year:

2003

Language:

english

File:

PDF, 383 KB

english, 2003

22

1,3-Butadiene: I. Review of metabolism and the implications to human health risk assessment

Kirman, Christopher R., Albertini, Richard J., Sweeney, Lisa M., Gargas, Michael L.

Journal:

Critical Reviews in Toxicology

Year:

2010

Language:

english

File:

PDF, 764 KB

english, 2010

23

Interpreting Estrogen Screening Assays in the Context of Potency and Human Exposure Relative to Natural Exposures to Phytoestrogens

Becker, Richard A., Hays, Sean M., Kirman, Christopher R., Aylward, Lesa L., Wise, Kimberly

Journal:

Birth Defects Research Part B: Developmental and Reproductive Toxicology

Year:

2014

Language:

english

File:

PDF, 148 KB

english, 2014

24

High concentrations of hexavalent chromium in drinking water alter iron homeostasis in F344 rats and B6C3F1 mice

Suh, Mina, Thompson, Chad M., Kirman, Christopher R., Carakostas, Michael C., Haws, Laurie C., Harris, Mark A., Proctor, Deborah M.

Journal:

Food and Chemical Toxicology

Year:

2014

Language:

english

File:

PDF, 1.05 MB

english, 2014

25

Safety assessment for ethanol-based topical antiseptic use by health care workers: Evaluation of developmental toxicity potential

Maier, Andrew, Ovesen, Jerald L., Allen, Casey L., York, Raymond G., Gadagbui, Bernard K., Kirman, Christopher R., Poet, Torka, Quiñones-Rivera, Antonio

Journal:

Regulatory Toxicology and Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.14 MB

english, 2015

26

The challenge of using read-across within the EU REACH regulatory framework; how much uncertainty is too much? Dipropylene glycol methyl ether acetate, an exemplary case study

Ball, Nicholas, Bartels, Michael, Budinsky, Robert, Klapacz, Joanna, Hays, Sean, Kirman, Christopher, Patlewicz, Grace

Journal:

Regulatory Toxicology and Pharmacology

Year:

2014

Language:

english

File:

PDF, 1.06 MB

english, 2014

27

Assessment of the mode of action underlying development of rodent small intestinal tumors following oral exposure to hexavalent chromium and relevance to humans

Thompson, Chad M., Proctor, Deborah M., Suh, Mina, Haws, Laurie C., Kirman, Christopher R., Harris, Mark A.

Journal:

Critical Reviews in Toxicology

Year:

2013

Language:

english

File:

PDF, 2.22 MB

english, 2013

28

Hexavalent chromium reduction kinetics in rodent stomach contents

Deborah M. Proctor, Mina Suh, Lesa L. Aylward, Christopher R. Kirman, Mark A. Harris, Chad M. Thompson, Hakan Gürleyük, Russell Gerads, Laurie C. Haws, Sean M. Hays

Journal:

Year:

2012

Language:

english

File:

PDF, 322 KB

english, 2012

29

Cancer risk assessment for 1,3-butadiene: Dose–response modeling from an epidemiological perspective

Robert L. Sielken Jr., Ciriaco Valdez-Flores, Michael L. Gargas, Christopher R. Kirman, M. Jane Teta, Elizabeth Delzell

Journal:

Chemico-Biological Interactions

Year:

2007

Language:

english

File:

PDF, 221 KB

english, 2007

30

Biomonitoring Equivalents for 2,2′,4,4′,5-pentabromodiphenylether (PBDE-99)

Kannan Krishnan, Therese Adamou, Lesa L. Aylward, Sean M. Hays, Christopher R. Kirman, Andy Nong

Journal:

Regulatory Toxicology and Pharmacology

Year:

2011

Language:

english

File:

PDF, 255 KB

english, 2011

31

Derivation of a drinking water equivalent level (DWEL) related to the maximum contaminant level goal for perfluorooctanoic acid (PFOA), a persistent water soluble compound

Robert G. Tardiff, M. Leigh Carson, Lisa M. Sweeney, Christopher R. Kirman, Yu-Mei Tan, Melvin Andersen, Christopher Bevan, Michael L. Gargas

Journal:

Food and Chemical Toxicology

Year:

2009

Language:

english

File:

PDF, 525 KB

english, 2009

32

Biomonitoring Equivalents for DDT/DDE

Christopher R. Kirman, Lesa L. Aylward, Sean M. Hays, Kannan Krishnan, Andy Nong

Journal:

Regulatory Toxicology and Pharmacology

Year:

2011

Language:

english

File:

PDF, 430 KB

english, 2011

33

Derivation of inhalation toxicity reference values for propylene oxide using mode of action analysis: Example of a threshold carcinogen

Sweeney, Lisa M., Kirman, Christopher R., Albertini, Richard J., Tan, Yu-Mei, Clewell, Harvey J., Filser, Johannes G., Csanády, György, Pottenger, Lynn H., Banton, Marcy I., Graham, Cynthia J., Andrew

Journal:

Critical Reviews in Toxicology

Year:

2009

Language:

english

File:

PDF, 1.23 MB

english, 2009

34

1,3-Butadiene: III. Assessing carcinogenic modes of action

Kirman, Christopher R., Albertini, Richard A., Gargas, Michael L.

Journal:

Critical Reviews in Toxicology

Year:

2010

Language:

english

File:

PDF, 886 KB

english, 2010

35

Approaches for describing and communicating overall uncertainty in toxicity characterizations: U.S. Environmental Protection Agency's Integrated Risk Information System (IRIS) as a case study

Beck, Nancy B., Becker, Richard A., Erraguntla, Neeraja, Farland, William H., Grant, Roberta L., Gray, George, Kirman, Christopher, LaKind, Judy S., Jeffrey Lewis, R., Nance, Patricia, Pottenger, Lynn

Journal:

Environment International

Year:

2016

Language:

english

File:

PDF, 4.16 MB

english, 2016

36

Biomonitoring Equivalents for di-isononyl phthalate (DINP)

Sean M. Hays, Lesa L. Aylward, Christopher R. Kirman, Kannan Krishnan, Andy Nong

Journal:

Regulatory Toxicology and Pharmacology

Year:

2011

Language:

english

File:

PDF, 286 KB

english, 2011

37

Assessment of margin of exposure based on biomarkers in blood: An exploratory analysis

Lesa L. Aylward, Richard A. Becker, Christopher R. Kirman, Sean M. Hays

Journal:

Regulatory Toxicology and Pharmacology

Year:

2011

Language:

english

File:

PDF, 629 KB

english, 2011

38

Biomonitoring Equivalents for deltamethrin

Lesa L. Aylward, Kannan Krishnan, Christopher R. Kirman, Andy Nong, Sean M. Hays

Journal:

Regulatory Toxicology and Pharmacology

Year:

2011

Language:

english

File:

PDF, 412 KB

english, 2011

39

The importance of problem formulations in risk assessment: A case study involving dioxin-contaminated soil

Dourson, Michael L., Gadagbui, Bernard, Griffin, Susan, Garabrant, David H., Haws, Laurie C., Kirman, Christopher, Tohyama, Chiharu

Journal:

Regulatory Toxicology and Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.28 MB

english, 2013

40

Human health screening level risk assessments of tertiary-butyl acetate (TBAC): Calculated acute and chronic reference concentration (RfC) and Hazard Quotient (HQ) values based on toxicity and exposure scenario evaluations

Bus, James S., Banton, Marcy I., Faber, Willem D., Kirman, Christopher R., McGregor, Douglas B., Pourreau, Daniel B.

Journal:

Critical Reviews in Toxicology

Year:

2015

Language:

english

File:

PDF, 1.04 MB

english, 2015

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